Product Description
SMTNL1 Antibody (Center) [APR30796G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This SMTNL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 amino acids from the Central region of human SMTNL1.
Cellular Localisation: Cytoplasm, myofibril. Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, M line Nucleus. Note=Colocalizes with MYH2. In its unphosphorylated state, localizes to the cytoplasm (By similarity) Phosphorylation at Ser-301 promotes translocation to the nucleus (By similarity) .
Molecular Weight: 52987
Clone: Polyclonal
Gene Name: SMTNL1
Gene ID: 219537
Function: Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity (By similarity) .
Summary: Tissue Location: Expressed in striated muscles, specifically in type 2a fibers (at protein level) .
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, FC
Dilution: WB--1:2000
Synonyms: Smoothelin-like protein 1, SMTNL1