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Product Description
TSSK4 Antibody (C-term) [APR30754G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This TSSK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-254 amino acids from the C-terminal region of human TSSK4.
Cellular Localisation: Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q9D411}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q9D411}. Note=In spermatozoa, present in the sperm head and in the flagellum. {ECO:0000250|UniProtKB:Q9D411}
Molecular Weight: 37454
Clone: Polyclonal
Gene Name: TSSK4 (HGNC:19825)
Gene ID: 283629
Function: Serine/threonine kinase which is involved in male germ cell development and in mature sperm function (By similarity) . May be involved in the Cre/Creb signaling pathway (By similarity) . Phosphorylates CREB1 on 'Ser-133' in vitro and can stimulate Cre/Creb pathway in cells (PubMed:15964553) . Phosphorylates CREM on 'Ser-116' in vitro (By similarity) . Phosphorylates ODF2 on 'Ser-95' (By similarity) .
Summary: Tissue Location: Expressed only in the testis.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P, IF
Dilution: WB--1:1000 IHC-P--1:100~500 IF--1:10~50
Synonyms: Testis-specific serine/threonine-protein kinase 4, TSK-4, TSSK-4, Testis-specific kinase 4, Serine/threonine-protein kinase 22E, TSSK4, C14orf20, STK22E, TSSK5
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