Product Description
ARHGAP22 Antibody (C-term) [APR15010G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This ARHGAP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 604-633 amino acids from the C-terminal region of human ARHGAP22.
Cellular Localisation: Cytoplasm. Nucleus. Note=Mainly cytoplasmic. Some fraction is nuclear (By similarity)
Molecular Weight: 76779
Clone: Polyclonal
Gene Name: ARHGAP22
Gene ID: 58504
Function: Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1- dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter (By similarity) .
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Rho GTPase-activating protein 22, Rho-type GTPase-activating protein 22, ARHGAP22, RHOGAP2