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Product Description
CALCRL Antibody (Center) [APR15224G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This CALCRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 340-367 amino acids from the Central region of human CALCRL.
Cellular Localisation: Cell membrane; Multi-pass membrane protein
Molecular Weight: 52929
Clone: Polyclonal
Gene Name: CALCRL
Gene ID: 10203
Function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity) . Receptor for adrenomedullin together with RAMP2 (PubMed:22102369, PubMed:30115739) . The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (PubMed:22102369, PubMed:30115739) .
Summary: Tissue Location: Predominantly expressed in the lung and heart.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: IHC-P-Leica, WB
Dilution: WB--1:2000
Synonyms: Calcitonin gene-related peptide type 1 receptor, CGRP type 1 receptor, Calcitonin receptor-like receptor, CALCRL, CGRPR
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