Product Description
CNTLN Antibody (N-term) [APR03782G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This CNTLN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-227 amino acids from the N-terminal region of human CNTLN.
Cellular Localisation: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Note=Colocalizes with gamma-tubulin during interphase and mitosis Appears to associate with the mother centriole during G1 phase and with daughter centrioles towards G1/S phase (By similarity) . Localizes to the proximal ends of the centrioles (PubMed:24554434) . Levels are high at interphase centrosomes but are reduced on mitotic spindle poles (PubMed:24554434) . {ECO:0000250|UniProtKB:A9ZSY0, ECO:0000269|PubMed:24554434}
Molecular Weight: 161571
Clone: Polyclonal
Gene Name: CNTLN
Gene ID: 54875
Function: Required for centrosome cohesion and recruitment of CEP68 to centrosomes.
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: IHC-P, WB
Dilution: WB--1:1000 IHC-P--1:100~500
Synonyms: Centlein, Centrosomal protein, CNTLN, C9orf101, C9orf39