Euro
USD
British Pound
NULL
![EDN1 Antibody (C-term) [APR07642G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/864278/1156345/logo__92149.1659788186__09760.1659860106.png?c=2 "EDN1 Antibody (C-term) [APR07642G]"){kind=logo}
![EDN1 Antibody (C-term) [APR07642G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/864278/1156345/logo__92149.1659788186__09760.1659860106.png?c=2 "EDN1 Antibody (C-term) [APR07642G]"){kind=logo}
Product Description
EDN1 Antibody (C-term) [APR07642G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This EDN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-203 amino acids from the C-terminal region of human EDN1.
Cellular Localisation: Secreted.
Molecular Weight: 24425
Clone: Polyclonal
Gene Name: EDN1
Gene ID: 1906
Function: Endothelins are endothelium-derived vasoconstrictor peptides (By similarity) . Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (PubMed:19086031) .
Summary: Tissue Location: Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: IHC-P, WB, IF
Dilution: IHC-P--1:100~500 WB--1:1000 IF--1:10~50
Synonyms: Endothelin-1, Preproendothelin-1, PPET1, Endothelin-1, ET-1, Big endothelin-1, EDN1
![EDN1 Antibody (C-term) [APR07642G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/864278/1156345/logo__92149.1659788186__09760.1659860106.png?c=2 "EDN1 Antibody (C-term) [APR07642G]"){kind=logo}
![Aurora-C Antibody (C-term) [APR32362G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/872607/1164674/logo__92149.1659788186__46763.1659868725.png?c=2 "Aurora-C Antibody (C-term) [APR32362G]"){kind=logo}