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Product Description
EDN1 Antibody (Center) [APR07643G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This EDN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-138 amino acids from the Central region of human EDN1.
Cellular Localisation: Secreted.
Molecular Weight: 24425
Clone: Polyclonal
Gene Name: EDN1
Gene ID: 1906
Function: Endothelins are endothelium-derived vasoconstrictor peptides (By similarity) . Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (PubMed:19086031) .
Summary: Tissue Location: Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P, IF, FC
Dilution: WB--1:500
Synonyms: Endothelin-1, Preproendothelin-1, PPET1, Endothelin-1, ET-1, Big endothelin-1, EDN1
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