Product Description
RREB1 Antibody (C-term) [AMM07668G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This RREB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1398-1424 amino acids from the C-terminal region of human RREB1.
Cellular Localisation: Nucleus speckle
Molecular Weight: 181420
Clone: Polyclonal
Gene Name: RREB1
Gene ID: 6239
Function: Transcription factor that binds specifically to the RAS- responsive elements (RRE) of gene promoters (PubMed:9305772, PubMed:15067362, PubMed:8816445, PubMed:10390538, PubMed:17550981) . Represses the angiotensinogen gene (PubMed:15067362) . Negatively regulates the transcriptional activity of AR (PubMed:17550981) . Potentiates the transcriptional activity of NEUROD1 (PubMed:12482979) . Promotes brown adipocyte differentiation (By similarity) . May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression (PubMed:8816445) .
Summary: Tissue Location: Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Ras-responsive element-binding protein 1, RREB-1, Finger protein in nuclear bodies, Raf-responsive zinc finger protein LZ321, Zinc finger motif enhancer-binding protein 1, Zep-1, RREB1, FINB