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Product Description
TRIM58 Antibody (C-term) [APR04379G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This TRIM58 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 457-486 amino acids from the C-terminal region of human TRIM58.
Cellular Localisation: N/A
Molecular Weight: 54766
Clone: Polyclonal
Gene Name: TRIM58
Gene ID: 25893
Function: E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization.
Summary: Tissue Location: Expressed in erythroblasts.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: E3 ubiquitin-protein ligase TRIM58, 632-, Protein BIA2, Tripartite motif-containing protein 58, TRIM58
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