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Product Description
UNC5D Antibody (Center) [APR13950G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This UNC5D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 483-511 amino acids from the Central region of human UNC5D.
Cellular Localisation: Cell membrane; Single-pass type I membrane protein
Molecular Weight: 105880
Clone: Polyclonal
Gene Name: UNC5D
Gene ID: 137970
Function: Receptor for the netrin NTN4 that promotes neuronal cell survival (By similarity) . Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity) . May play a role in apoptosis in response to DNA damage (PubMed:24691657) . It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed:24519068) . Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell (By similarity) .
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Netrin receptor UNC5D, Protein unc-5 homolog 4, Protein unc-5 homolog D, UNC5D, KIAA1777, UNC5H4
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