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![(Mouse) Pou5f1 Antibody (N-term) [AMM08728G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/869815/1161882/logo__92149.1659788186__59541.1659865940.png?c=2 "(Mouse) Pou5f1 Antibody (N-term) [AMM08728G]"){kind=logo}
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Product Description
(Mouse) Pou5f1 Antibody (N-term) [AMM08728G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: M
Specificity: This Mouse Pou5f1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 86-119 amino acids from the N-terminal region of Mouse Pou5f1.
Cellular Localisation: Cytoplasm {ECO:0000250|UniProtKB:Q01860}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE- ProRule:PRU00530, ECO:0000269|PubMed:17496161, ECO:0000269|PubMed:17525163, ECO:0000269|PubMed:29153991} Note=Expressed in a diffuse and slightly punctuate pattern (By similarity) . Colocalizes with MAPK8 and MAPK9 in the nucleus (PubMed:29153991) . {ECO:0000250|UniProtKB:Q01860, ECO:0000269|PubMed:29153991}
Molecular Weight: 38216
Clone: Polyclonal
Gene Name: Pou5f1
Gene ID: 18999
Function: Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3') (PubMed:1972777, PubMed:1690859, PubMed:1967980, PubMed:17525163, PubMed:23376973) . Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (PubMed:15863505, PubMed:17097055, PubMed:17496161, PubMed:19740739) . Critical for early embryogenesis and for embryonic stem cell pluripotency (PubMed:1972777, PubMed:1690859, PubMed:17496161, PubMed:18662995, PubMed:19740739, PubMed:29153991, PubMed:23376973) .
Summary: Tissue Location: Expressed the totipotent and pluripotent stem cells of the pregastrulation embryo. Also expressed in primordial germ cells and in the female germ line. Absent from adult tissues
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB, IHC-P
Dilution: IHC-P--1:100~500 WB--1:2000
Synonyms: POU domain, class 5, transcription factor 1, NF-A3, Octamer-binding protein 3, Oct-3, Octamer-binding protein 4, Oct-4, Octamer-binding transcription factor 3, OTF-3, Pou5f1, Oct-3, Oct-4, Otf-3, Otf3
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![(Mouse) Pou5f1 Antibody (Center) [AMM08727G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/869801/1161868/logo__92149.1659788186__09567.1659865930.png?c=2 "(Mouse) Pou5f1 Antibody (Center) [AMM08727G]"){kind=logo}