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Product Description
MPP2 Antibody (C-Term) [APR17455G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: M
Specificity: This MPP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 398-419 amino acids from human MPP2.
Cellular Localisation: Cytoplasm, cytoskeleton. Membrane Cell projection, dendrite {ECO:0000250|UniProtKB:Q9WV34}. Cell junction, synapse, postsynaptic density {ECO:0000250|UniProtKB:Q9WV34} Note=Prominently expressed in the postsynaptic densities of dendritic spines, is also detected in dendritic shafts {ECO:0000250|UniProtKB:Q9WV34}
Molecular Weight: 64581
Clone: Polyclonal
Gene Name: MPP2 (HGNC:7220)
Gene ID: 4355
Function: Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density (By similarity) . In CA1 pyramidal neurons, required for synaptic KCNN2- containing channel function and long-term potentiation expression (By similarity) . Seems to negatively regulate SRC function in epithelial cells (PubMed:19665017) .
Summary: N/A
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: MAGUK p55 subfamily member 2, Discs large homolog 2, Protein MPP2, MPP2, DLG2
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