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Product Description
ZNF238 Antibody (C-Term) [APR33400G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: M
Specificity: This ZNF238 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 318-331 amino acids from human ZNF238.
Cellular Localisation: Nucleus. Note=Associates with condensed chromatin
Molecular Weight: 58354
Clone: Polyclonal
Gene Name: ZBTB18
Gene ID: 10472
Function: Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus.
Summary: Tissue Location: Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Zinc finger and BTB domain-containing protein 18, 58 kDa repressor protein, Transcriptional repressor RP58, Translin-associated zinc finger protein 1, TAZ-1, Zinc finger protein 238, Zinc finger protein C2H2-171, ZBTB18, RP58, TAZ1, ZNF238
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