Euro
USD
British Pound
NULL
![B-RAF Antibody (S445) [APR32503G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/872748/1164815/logo__92149.1659788186__08333.1659868782.png?c=2 "B-RAF Antibody (S445) [APR32503G]"){kind=logo}
![B-RAF Antibody (S445) [APR32503G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/872748/1164815/logo__92149.1659788186__08333.1659868782.png?c=2 "B-RAF Antibody (S445) [APR32503G]"){kind=logo}
Product Description
B-RAF Antibody (S445) [APR32503G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This B-RAF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 424-453 amino acids from human B-RAF.
Cellular Localisation: Nucleus. Cytoplasm. Cell membrane. Note=Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes.
Molecular Weight: 84437
Clone: Polyclonal
Gene Name: BRAF (HGNC:1097)
Gene ID: 673
Function: Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable) . Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway (PubMed:21441910, PubMed:29433126) . May play a role in the postsynaptic responses of hippocampal neurons (PubMed:1508179) .
Summary: Tissue Location: Brain and testis.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P, IF, FC
Dilution: IF--1:25 FC--1:25 WB--1:2000 WB--1:1000 IHC-P--1:100~500 IF--1:10~50
Synonyms: Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1, BRAF, BRAF1, RAFB1
![B-RAF Antibody (S445) [APR32503G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/872748/1164815/logo__92149.1659788186__08333.1659868782.png?c=2 "B-RAF Antibody (S445) [APR32503G]"){kind=logo}
