Product Description
CLCN1 Antibody (N-Term) [APR33597G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This CLCN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-66 amino acids from the human region of human CLCN1.
Cellular Localisation: Cell membrane; Multi-pass membrane protein
Molecular Weight: 108626
Clone: Polyclonal
Gene Name: CLCN1 (HGNC:2019)
Gene ID: 1180
Function: Voltage-gated chloride channel (PubMed:8112288, PubMed:9122265, PubMed:12456816) . Plays an important role in membrane repolarization in skeletal muscle cells after muscle contraction. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons (Probable) . The absence of conserved gating glutamate residues is typical for family members that function as channels (Probable) .
Summary: Tissue Location: Predominantly expressed in skeletal muscles.
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB, FC
Dilution: FC--1:25 WB--1:2000
Synonyms: Chloride channel protein 1, ClC-1, Chloride channel protein, skeletal muscle, CLCN1, CLC1