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Product Description
DHX30 Antibody (N-term) [APR31490G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This DHX30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-53 amino acids from the N-terminal region of human DHX30.
Cellular Localisation: Cytoplasm. Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid. Note=Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids (PubMed:16825194, PubMed:25683715) . Relocalizes to stress granules upon heat stress (PubMed:29100085) .
Molecular Weight: 133938
Clone: Polyclonal
Gene Name: DHX30
Gene ID: 22907
Function: RNA-dependent helicase (PubMed:29100085) . Plays an important role in the assembly of the mitochondrial large ribosomal subunit (PubMed:25683715, PubMed:29100085) . Required for optimal function of the zinc-finger antiviral protein ZC3HAV1 (By similarity) . Associates with mitochondrial DNA (PubMed:18063578) . Involved in nervous system development and differentiation through its involvement in the up- regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD (By similarity) .
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Putative ATP-dependent RNA helicase DHX30, DEAH box protein 30, DHX30, DDX30, KIAA0890
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