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Product Description
DLX1 Antibody (Center) [APR33569G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This DLX1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 84-118 amino acids from the Central region of human DLX1.
Cellular Localisation: Nucleus.
Molecular Weight: 27320
Clone: Polyclonal
Gene Name: DLX1
Gene ID: 1745
Function: Plays a role as a transcriptional activator or repressor (PubMed:14671321) . Inhibits several cytokine signaling pathways, such as TGFB1, activin-A/INHBA and BMP4 by interfering with the transcriptional stimulatory activity of transcription factors, such as MSX2, FAST2, SMAD2 and SMAD3 during hematopoietic cell differentiation (PubMed:14671321) . Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina (By similarity) . Likely to play a regulatory role in the development of the ventral forebrain (By similarity) . May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions (By similarity) .
Summary: Tissue Location: Expressed in hematopoietic cell lines.
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB, FC
Dilution: FC--1:25 WB--1:2000
Synonyms: Homeobox protein DLX-1, DLX1
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