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Product Description
DNASE1L2 Antibody (C-Term) [APR33394G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This DNASE1L2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 199-229 amino acids from human DNASE1L2.
Cellular Localisation: Cytoplasm. Secreted
Molecular Weight: 32853
Clone: Polyclonal
Gene Name: DNASE1L2
Gene ID: 1775
Function: Divalent cation-dependent acid DNA endonuclease involved in the breakdown of the nucleus during corneocyte formation of epidermal keratinocytes. May play an immune role by eliminating harmful DNA released into the extracellular environment by damaged epidermal cells.
Summary: Tissue Location: Preferentially expressed in the skin and up- regulated during keratinocytes differentiation. Highly abundant (at protein level) in the stratum granulosum
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Deoxyribonuclease-1-like 2, 3.1.21.-, DNase I homolog protein DHP1, Deoxyribonuclease I-like 2, DNase I-like 2, DNASE1L2, DHP1, DNAS1L2
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