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Product Description
MARCO Antibody (N-term) [APR32748G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This MARCO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids of human MARCO.
Cellular Localisation: Cell membrane; Single-pass type II membrane protein
Molecular Weight: 52658
Clone: Polyclonal
Gene Name: MARCO
Gene ID: 8685
Function: Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria (PubMed:9468508) . Also plays a role in binding of unopsonized particles by alveolar macrophages (By similarity) . Binds to the secretoglobin SCGB3A2 (PubMed:12847263) .
Summary: Tissue Location: Expressed in alveolar macrophages (at protein level) . Detected in macrophages from various tissues including thymus, kidney, Kupffer cells of liver, and spleen (PubMed:9468508)
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, FC, IHC-P
Dilution: WB--1:500
Synonyms: Macrophage receptor MARCO, Macrophage receptor with collagenous structure, Scavenger receptor class A member 2, MARCO, SCARA2
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