Product Description
Phospho-PBK/TOPK (Thr9) Antibody [APR33504G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This Phospho-PBK/TOPK (Thr9) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2-35 amino acids from the human Phospho-PBK/TOPK.
Cellular Localisation: N/A
Molecular Weight: 36085
Clone: Polyclonal
Gene Name: PBK
Gene ID: 55872
Function: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin- induced DNA damage.
Summary: Tissue Location: Expressed in the testis and placenta. In the testis, restrictedly expressed in outer cell layer of seminiferous tubules.
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:4000
Synonyms: Lymphokine-activated killer T-cell-originated protein kinase, 2.7.12.2, Cancer/testis antigen 84, CT84, MAPKK-like protein kinase, Nori-3, PDZ-binding kinase, Spermatogenesis-related protein kinase, SPK, T-LAK cell-originated protein kinase, PBK, TOPK