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Product Description
PRRT2 Antibody (Center) [APR31562G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This PRRT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-233 amino acids from the Central region of human PRRT2.
Cellular Localisation: Cell membrane; Single-pass membrane protein {ECO:0000250|UniProtKB:E9PUL5}. Cell junction, synapse, presynaptic cell membrane {ECO:0000250|UniProtKB:E9PUL5}; Single-pass membrane protein {ECO:0000250|UniProtKB:E9PUL5}. Cell junction, synapse {ECO:0000250|UniProtKB:E9PUL5}. Cell projection, axon. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:D3ZFB6}. Cell junction, synapse, postsynaptic density membrane {ECO:0000250|UniProtKB:D3ZFB6}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:D3ZFB6}
Molecular Weight: 34945
Clone: Polyclonal
Gene Name: PRRT2
Gene ID: 112476
Function: As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca (2+) -sensing. In the cerebellum, may inhibit SNARE complex formation and downregulate short-term facilitation.
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, FC
Dilution: FC--1:25 WB--1:2000
Synonyms: Proline-rich transmembrane protein 2, Dispanin subfamily B member 3, DSPB3, PRRT2
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