Euro
USD
British Pound
NULL
![RQCD1 Antibody (Center) [APR31593G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/871838/1163905/logo__92149.1659788186__22125.1659868227.png?c=2 "RQCD1 Antibody (Center) [APR31593G]"){kind=logo}
![RQCD1 Antibody (Center) [APR31593G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/871838/1163905/logo__92149.1659788186__22125.1659868227.png?c=2 "RQCD1 Antibody (Center) [APR31593G]"){kind=logo}
Product Description
RQCD1 Antibody (Center) [APR31593G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This RQCD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from the Central region of human RQCD1.
Cellular Localisation: Nucleus {ECO:0000250|UniProtKB:Q9JKY0}. Cytoplasm, P-body {ECO:0000250|UniProtKB:Q9JKY0}. Note=NANOS2 promotes its localization to P-body. {ECO:0000250|UniProtKB:Q9JKY0}
Molecular Weight: 33631
Clone: Polyclonal
Gene Name: CNOT9 (HGNC:10445)
Gene ID: 9125
Function: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down- regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation (By similarity) . Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all.
Summary: Tissue Location: Detected in spleen, thymus, prostate, testis, ovary and intestine.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:500
Synonyms: Cell differentiation protein RCD1 homolog, Rcd-1, CCR4-NOT transcription complex subunit 9, RQCD1, CNOT9, RCD1
![RQCD1 Antibody (Center) [APR31593G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/871838/1163905/logo__92149.1659788186__22125.1659868227.png?c=2 "RQCD1 Antibody (Center) [APR31593G]"){kind=logo}
