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Product Description
WDR51B Antibody (C-term) [APR33333G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This WDR51B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 386-417 amino acids from the C-terminal region of human WDR51B.
Cellular Localisation: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, spindle pole. Note=Component of both mother and daughter centrioles (PubMed:32060285) . Localizes to the basal body and centriole adjacent to the connecting cilium of photoreceptors and in synapses of the outer plexiform layer. {ECO:0000250|UniProtKB:Q8BHD1, ECO:0000269|PubMed:32060285}
Molecular Weight: 53668
Clone: Polyclonal
Gene Name: POC1B (HGNC:30836)
Gene ID: 282809
Function: Plays an important role in centriole assembly and/or stability and ciliogenesis (PubMed:20008567, PubMed:32060285) . Involved in early steps of centriole duplication, as well as in the later steps of centriole length control (PubMed:19109428) . Acts in concert with POC1A to ensure centriole integrity and proper mitotic spindle formation (PubMed:32060285) . Required for primary cilia formation, ciliary length and also cell proliferation (PubMed:23015594) . Required for retinal integrity (PubMed:25044745) .
Summary: Tissue Location: Expressed in the retina.
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: POC1 centriolar protein homolog B, Pix1, Proteome of centriole protein 1B, WD repeat-containing protein 51B, POC1B, WDR51B
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