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Product Description
WNT10B Antibody (Center) [APR32308G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, Rat
Specificity: This WNT10B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-222 amino acids from the Central region of human WNT10B.
Cellular Localisation: Secreted, extracellular space, extracellular matrix. Secreted
Molecular Weight: 43000
Clone: Polyclonal
Gene Name: WNT10B
Gene ID: 7480
Function: Member of the Wnt ligand gene family that encodes for secreted proteins, which activate the Wnt signaling cascade. Specifically activates canonical Wnt/beta-catenin signaling and thus triggers beta-catenin/LEF/TCF-mediated transcriptional programs. Involved in signaling networks controlling stemness, pluripotency and cell fate decisions. Acts in the immune system, mammary gland, adipose tissue, bone and skin.
Summary: Tissue Location: Detected in most adult tissues. Highest levels were found in heart and skeletal muscle. Low levels are found in brain
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P, FC
Dilution: WB--1:2000
Synonyms: Protein Wnt-10b, Protein Wnt-12, WNT10B, WNT12
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