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Product Description
Zebrafish wnt8a Antibody (Center) [APR33338G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: Zf
Specificity: This Zebrafish wnt8a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 135-170 amino acids from the Central region of Zebrafish wnt8a.
Cellular Localisation: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q9H1J5}. Secreted {ECO:0000250|UniProtKB:Q9H1J5}
Molecular Weight: 40289
Clone: Polyclonal
Gene Name: wnt8a
Gene ID: 30122
Function: Ligand for members of the frizzled family of seven transmembrane receptors (Probable) . Required for mesoderm and neural ectoderm patterning during gastrulation (PubMed:11703928) . Involved in axis formation during embryonic development, via activation of canonical Wnt/CTNNB1 signaling (PubMed:11703928, PubMed:25371059) . May be involved in the specification of the spatial patterns of expression of Gsc and other regulatory genes leading to the establishment of the embryonic axis (PubMed:7600994) .
Summary: Tissue Location: Expressed in the margin of the pregastrula embryo destined to be the future mesoderm.
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000-1:2000
Synonyms: Protein Wnt-8a, wnt8a, wnt-8, wnt8
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