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![ZFYVE20 Antibody (N-Term) [APR33174G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/873419/1165486/logo__92149.1659788186__84183.1659869053.png?c=2 "ZFYVE20 Antibody (N-Term) [APR33174G]"){kind=logo}
![ZFYVE20 Antibody (N-Term) [APR33174G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/873419/1165486/logo__92149.1659788186__84183.1659869053.png?c=2 "ZFYVE20 Antibody (N-Term) [APR33174G]"){kind=logo}
Product Description
ZFYVE20 Antibody (N-Term) [APR33174G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This ZFYVE20 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 41-65 amino acids from the human region of human ZFYVE20.
Cellular Localisation: Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor Note=Enriched in endosomes that are in close proximity to clathrin- enriched regions at the cell surface.
Molecular Weight: 88870
Clone: Polyclonal
Gene Name: RBSN (HGNC:20759)
Gene ID: 64145
Function: Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3) (PubMed:11062261, PubMed:11788822, PubMed:15020713) . Plays a role in the recycling of transferrin receptor to the plasma membrane (PubMed:22308388) .
Summary: N/A
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000 WB--1:8000
Synonyms: Rabenosyn-5, 110 kDa protein, FYVE finger-containing Rab5 effector protein rabenosyn-5, RAB effector RBSN {ECO:0000312|HGNC:HGNC:20759}, Zinc finger FYVE domain-containing protein 20, RBSN (HGNC:20759)
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