Euro
USD
British Pound
NULL
![BTBD1 Antibody (Center) [APR11013G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/868049/1160116/logo__92149.1659788186__79585.1659864213.png?c=2 "BTBD1 Antibody (Center) [APR11013G]"){kind=logo}
![BTBD1 Antibody (Center) [APR11013G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/868049/1160116/logo__92149.1659788186__79585.1659864213.png?c=2 "BTBD1 Antibody (Center) [APR11013G]"){kind=logo}
Product Description
BTBD1 Antibody (Center) [APR11013G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This BTBD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-322 amino acids from the Central region of human BTBD1.
Cellular Localisation: Cytoplasm. Note=Localizes to punctate or elongated cytoplasmic bodies.
Molecular Weight: 52771
Clone: Polyclonal
Gene Name: BTBD1
Gene ID: 53339
Function: Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:14528312) . Seems to regulate expression levels and/or subnuclear distribution of TOP1, via an unknown mechanism (By similarity) . May play a role in mesenchymal differentiation where it promotes myogenic differentiation and suppresses adipogenesis (By similarity) .
Summary: Tissue Location: Ubiquitous; highest levels in testes, heart and skeletal muscle.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, FC
Dilution: WB--1:1000 FC--1:10~50
Synonyms: BTB/POZ domain-containing protein 1, Hepatitis C virus NS5A-transactivated protein 8, HCV NS5A-transactivated protein 8, BTBD1, C15orf1, NS5ATP8
![BTBD1 Antibody (Center) [APR11013G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/868049/1160116/logo__92149.1659788186__79585.1659864213.png?c=2 "BTBD1 Antibody (Center) [APR11013G]"){kind=logo}
