Euro
USD
British Pound
NULL
![CYP21A2 Antibody (N-term) [APG02861G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/868381/1160448/logo__92149.1659788186__40724.1659864354.png?c=2 "CYP21A2 Antibody (N-term) [APG02861G]"){kind=logo}
![CYP21A2 Antibody (N-term) [APG02861G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/868381/1160448/logo__92149.1659788186__40724.1659864354.png?c=2 "CYP21A2 Antibody (N-term) [APG02861G]"){kind=logo}
Product Description
CYP21A2 Antibody (N-term) [APG02861G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This CYP21A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-87 amino acids from the N-terminal region of human CYP21A2.
Cellular Localisation: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein
Molecular Weight: 55887
Clone: Polyclonal
Gene Name: CYP21A2
Gene ID: 1589
Function: A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11- deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids (PubMed:25855791, PubMed:10602386, PubMed:16984992, PubMed:22014889, PubMed:27721825) . Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (PubMed:25855791) .
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Steroid 21-hydroxylase, 21-OHase, Cytochrome P-450c21, Cytochrome P450 21, Cytochrome P450 XXI, Cytochrome P450-C21, Cytochrome P450-C21B, CYP21A2, CYP21, CYP21B
![CYP21A2 Antibody (N-term) [APG02861G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/868381/1160448/logo__92149.1659788186__40724.1659864354.png?c=2 "CYP21A2 Antibody (N-term) [APG02861G]"){kind=logo}
![CYP21A2 Antibody (Center) [APR07096G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/868382/1160449/logo__92149.1659788186__29839.1659864354.png?c=2 "CYP21A2 Antibody (Center) [APR07096G]"){kind=logo}
