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![Deoxyguanosine Kinase (DGUOK) Antibody (C-term) [APR15720G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/867924/1159991/logo__92149.1659788186__47836.1659864161.png?c=2 "Deoxyguanosine Kinase (DGUOK) Antibody (C-term) [APR15720G]"){kind=logo}
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Product Description
Deoxyguanosine Kinase (DGUOK) Antibody (C-term) [APR15720G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This Deoxyguanosine Kinase (DGUOK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-271 amino acids from the C-terminal region of human Deoxyguanosine Kinase (DGUOK) .
Cellular Localisation: Mitochondrion {ECO:0000250|UniProtKB:Q9QX60}.
Molecular Weight: 32056
Clone: Polyclonal
Gene Name: DGUOK
Gene ID: 1716
Function: Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine (PubMed:8692979, PubMed:8706825, PubMed:11687801, PubMed:17073823, PubMed:23043144) . In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs (By similarity) . Widely used as target of antiviral and chemotherapeutic agents.
Summary: Tissue Location: Ubiquitous. Highest expression in muscle, brain, liver and lymphoid tissues.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Deoxyguanosine kinase, mitochondrial, dGK, DGUOK, DGK
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