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Product Description
GPR17 Antibody (Center) [APG03372G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This GPR17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-258 amino acids from the Central region of human GPR17.
Cellular Localisation: Cell membrane; Multi-pass membrane protein.
Molecular Weight: 40989
Clone: Polyclonal
Gene Name: GPR17
Gene ID: 2840
Function: Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs) . Signals through G (i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.
Summary: Tissue Location: Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P, FC
Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50
Synonyms: Uracil nucleotide/cysteinyl leukotriene receptor, UDP/CysLT receptor, G-protein coupled receptor 17, P2Y-like receptor, R12, GPR17
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