Product Description
HAS1 Antibody (Center) [APR14081G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This HAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-193 amino acids from the Central region of human HAS1.
Cellular Localisation: Membrane; Multi-pass membrane protein
Molecular Weight: 64832
Clone: Polyclonal
Gene Name: HAS1
Gene ID: 3036
Function: Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction. Also able to catalyze the synthesis of chito- oligosaccharide depending on the substrate (By similarity) .
Summary: Tissue Location: Widely expressed. Highly expressed in ovary followed by spleen, thymus, prostate, testes and large intestine Weakly expressed in small intestine.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Hyaluronan synthase 1, Hyaluronate synthase 1, Hyaluronic acid synthase 1, HA synthase 1, HuHAS1, HAS1, HAS