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![Mouse Camkk2 Antibody (N-term) [APR04046G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/865274/1157341/logo__92149.1659788186__66660.1659862398.png?c=2 "Mouse Camkk2 Antibody (N-term) [APR04046G]"){kind=logo}
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Product Description
Mouse Camkk2 Antibody (N-term) [APR04046G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M, Rat
Specificity: This Mouse Camkk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-71 amino acids from the N-terminal region of mouse Camkk2.
Cellular Localisation: Nucleus {ECO:0000250|UniProtKB:Q96RR4}. Cytoplasm {ECO:0000250|UniProtKB:Q96RR4}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q96RR4}. Note=Predominantly nuclear in unstimulated cells, relocalizes into cytoplasm and neurites after forskolin induction. {ECO:0000250|UniProtKB:Q96RR4}
Molecular Weight: 64618
Clone: Polyclonal
Gene Name: Camkk2
Gene ID: 207565
Function: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK4 and CAMK1D (By similarity) . Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca (2+) signals (By similarity) . May play a role in neurite growth. Isoform 2 may promote neurite elongation, while isoform 1 may promoter neurite branching (By similarity) . May be involved in hippocampal activation of CREB1.
Summary: Tissue Location: Expressed in all tissues tested. A differential expression pattern compared to CAMKK1 is observed in the brain
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Calcium/calmodulin-dependent protein kinase kinase 2, CaM-KK 2, CaM-kinase kinase 2, CaMKK 2, Calcium/calmodulin-dependent protein kinase kinase beta, CaM-KK beta, CaM-kinase kinase beta, CaMKK beta, Camkk2, Kiaa0787
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