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Product Description
PLAUR Antibody (C-term) [APR04624G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This PLAUR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 273-305 amino acids from the C-terminal region of human PLAUR.
Cellular Localisation: Cell membrane. Cell projection, invadopodium membrane Note=Colocalized with FAP (seprase) preferentially at the cell surface of invadopodia membrane in a cytoskeleton-, integrin- and vitronectin- dependent manner. [Isoform 2]: Secreted {ECO:0000250|UniProtKB:P49616}
Molecular Weight: 36978
Clone: Polyclonal
Gene Name: PLAUR
Gene ID: 5329
Function: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Summary: Tissue Location: Expressed in neurons of the rolandic area of the brain (at protein level) . Expressed in the brain
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB, IHC-P
Dilution: IHC-P--1:100~500 WB--1:1000
Synonyms: Urokinase plasminogen activator surface receptor, U-PAR, uPAR, Monocyte activation antigen Mo3, CD87, PLAUR, MO3, UPAR
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