Euro
USD
British Pound
NULL
![XYLT1 Antibody (N-term) [AMM08715G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/864547/1156614/logo__92149.1659788186__71201.1659860216.png?c=2 "XYLT1 Antibody (N-term) [AMM08715G]"){kind=logo}
![XYLT1 Antibody (N-term) [AMM08715G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/864547/1156614/logo__92149.1659788186__71201.1659860216.png?c=2 "XYLT1 Antibody (N-term) [AMM08715G]"){kind=logo}
Product Description
XYLT1 Antibody (N-term) [AMM08715G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M, Rat
Specificity: This XYLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-155 amino acids from the N-terminal region of human XYLT1.
Cellular Localisation: Golgi apparatus membrane; Single-pass type II membrane protein. Secreted Note=Detected predominantly in the Golgi apparatus
Molecular Weight: 107569
Clone: Polyclonal
Gene Name: XYLT1
Gene ID: 64131
Function: Catalyzes the first step in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D- xylose from UDP-D-xylose to specific serine residues of the core protein (PubMed:15461586, PubMed:17189265, PubMed:24581741, PubMed:23982343) . Required for normal embryonic and postnatal skeleton development, especially of the long bones (PubMed:24581741, PubMed:23982343) . Required for normal maturation of chondrocytes during bone development, and normal onset of ossification (By similarity) .
Summary: Tissue Location: Widely expressed. Expressed at higher level in placenta, kidney and pancreas. Weakly expressed in skeletal muscle
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, FC
Dilution: WB--1:1000
Synonyms: Xylosyltransferase 1, Peptide O-xylosyltransferase 1, Xylosyltransferase I, XT-I, XylT-I, XYLT1, XT1
![XYLT1 Antibody (N-term) [AMM08715G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/864547/1156614/logo__92149.1659788186__71201.1659860216.png?c=2 "XYLT1 Antibody (N-term) [AMM08715G]"){kind=logo}
