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Product Description
CCT6A Antibody | 19-097 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-250 of human CCT6A (NP_001753.1) .
Research Area: Signal Transduction
Tested Application: WB, IHC
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: BT-474
Positive Control 2: U-251MG
Positive Control 3: HeLa
Positive Control 4: SKOV3
Positive Control 5: Mouse kidney
Positive Control 6: Mouse brain
Molecular Weight: Observed: 58kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: CCT-zeta, CCT-zeta-1, CCT6, Cctz, HTR3, MoDP-2, TCP-1-zeta, TCP2TCPZ, TTCP2T-complex protein 1 subunit zeta, T-complex protein 1, zeta subunit, acute morphine dependence related protein 2, amino acid transport defect-complementing, chaperonin containing T-complex subunit 6, chaperonin containing TCP1, subunit 6A (zeta 1) , histidine transport regulator 3
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT) , also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located.
