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Product Description
GMPS Antibody | 22-346 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 394-693 of human GMPS (NP_003866.1) .
Research Area: Other
Tested Application: WB, IP
Application: WB: 1:500 - 1:2000
IP: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: MCF-7
Positive Control 2: SKOV3
Positive Control 3: HL-60
Positive Control 4: U-251MG
Positive Control 5: Mouse heart
Positive Control 6: Mouse kidney
Molecular Weight: Observed: 80kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: GMPS,
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1) , which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.
