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Product Description
MC2R Antibody | 18-905 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant protein of human MC2R
Research Area: Cancer, Neuroscience, Signal Transduction
Tested Application: WB, IHC
Application: WB: 1:1000 - 1:2000
IHC: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: Raji
Positive Control 2: Mouse kidney
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 37kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: MC2R, melanocortin 2 receptor (adrenocorticotropic hormone) , ACTHR, MGC125798, ACTH receptor, MC2 receptor, adrenocorticotropic hormone receptor, corticotropin receptor, melanocortin 2 receptor
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC) . MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene.
