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![IL-6 Antibody [2M8M3]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/572586/805724/porsci_lo__79508.1648973713__01085.1649090928.png?c=2 "IL-6 Antibody [2M8M3]")
![IL-6 Antibody [2M8M3]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/572586/805724/porsci_lo__79508.1648973713__01085.1649090928.png?c=2 "IL-6 Antibody [2M8M3]")
Product Description
IL-6 Antibody [2M8M3] | 11-094 | ProSci
Host: Rabbit
Reactivity: Virus
Homology: N/A
Immunogen: E. coli-derived human IL-6 protein, amino acids Pro29-Met212
Research Area: Infectious Disease, COVID-19
Tested Application: E
Application: Human IL-6 Sandwich Immunoassay:
ELISA Capture: Recommended Concentration: 1-4ug/mL, Sample: Human IL-6 Monoclonal Antibody, Rabbit MAb (CAP)
ELISA Detection: Recommended Concentration: 0.03-0.15ug/mL, Sample: Human IL-6 Monoclonal Antibody, Rabbit MAb (DET)
Standard: Recommended Concentration: 0.78-50pg/mL, Sample: Recombinant Human IL6 Protein
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Affinity Purified, Endotoxin Level: < 1.0 EU/ug of the protein by LAL method.
Clonality: Recombinant Monoclonal
Clone: 2M8M3
Isotype: Rabbit IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied as a 0.2um filtered solution in PBS, pH 7.4.
Concentration: 1mg/ml
Storage Condition: This antibody can be stored at 2˚C to -8˚C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20˚C to -80˚C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Alternate Name: CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable) . The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable) .
![IL-6 Antibody [2M8M3]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/572586/805724/porsci_lo__79508.1648973713__01085.1649090928.png?c=2 "IL-6 Antibody [2M8M3]")
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