Product Description
Seasonal H1N1 Nonstructural Protein 1 Antibody | 5357 | ProSci
Host: Rabbit
Reactivity: Virus
Homology: N/A
Immunogen: NS1 antibody was raised against a synthetic peptide from the seasonal Influenza NS1 protein.
The immunogen is located within the last 50 amino acids of Seasonal H1N1 Nonstructural Protein 1.
Research Area: Infectious Disease
Tested Application: E
Application: NS1 antibody can be used for the detection of the NS1 protein from the H1N1 strain of Seasonal Influenza A in ELISA.
Specificiy: This antibody is specific for the seasonal H1N1 influenza NS1 and will not recognize the corresponding NS1 sequence from the Swine-Origin H1N1 influenza (A/California/04/2009 (H1N1) ) .
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Seasonal H1N1 Nonstructural Protein 1 Antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Seasonal H1N1 Nonstructural Protein 1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Condition: Seasonal H1N1 Nonstructural Protein 1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: Seasonal H1N1 Nonstructural Protein 1 Antibody:
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Seasonal H1N1 Nonstructural Protein 1 Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from patients in Mexico and the United States. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2'-5'OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the anti-viral protein kinase PKR.