Product Description
Seasonal H1N1 Nucleocapsid Protein Antibody | 5361 | ProSci
Host: Rabbit
Reactivity: Virus
Homology: N/A
Immunogen: NP antibody was raised against a synthetic peptide from the seasonal H1N1 NP protein.
The immunogen is located within amino acids 350 - 400 of Seasonal H1N1 Nucleocapsid Protein.
Research Area: Infectious Disease
Tested Application: E
Application: NP antibody can be used for the detection of the NP protein from the H1N1 strain of Seasonal Influenza A in ELISA.
Specificiy: This antibody is specific for the seasonal H1N1 influenza NP and will not recognize the corresponding NP sequence from the swine-origin H1N1 influenza (A/California/14/2009 (H1N1) ) .
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Seasonal H1N1 Nucleocapsid Protein Antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Seasonal H1N1 Nucleocapsid Protein Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Condition: Seasonal H1N1 Nucleocapsid Protein antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: Seasonal H1N1 Nucleocapsid Protein Antibody:
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Seasonal H1N1 Nucleocapsid Protein Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from patients in Mexico and the United States. The influenza A virus polymerase transcribes and replicates eight virion RNA (vRNA) segments, among which the nucleocapsid protein (NP) , thought to control whether mRNA or cRNA is produced. The nucleoprotein (NP) , which has multiple functions during the virus life cycle, possesses regions that are highly conserved among influenza A, B, and C viruses. It was recently found several NP mutations that affected the efficient incorporation of multiple viral-RNA (vRNA) segments into progeny virions even though a single vRNA segment was incorporated efficiently. This indicates that the respective conserved amino acids in NP may be critical for the assembly and/or incorporation of sets of eight vRNA segments.