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Product Description
Sin Nombre Virus Glycoprotein 2 Antibody | 7683 | ProSci
Host: Rabbit
Reactivity: Virus
Homology: N/A
Immunogen: Sin Nombre virus glycoprotein 2 antibody was raised against a 16 amino acid peptide near the center of the Sin Nombre virus glycoprotein.
The immunogen is located within amino acids 670 - 720 of Sin Nombre Virus Glycoprotein 2.
Research Area: Infectious Disease
Tested Application: E
Application: Sin Nombre virus glycoprotein 2 antibody can detect 10ng Sin Nombre virus glycoprotein 2 peptide in ELISA at 1 μg/ml.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Sin Nombre virus glycoprotein 2 antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Sin Nombre virus glycoprotein 2 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Condition: Sin Nombre Glycoprotein 2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Alternate Name: Sin Nombre Virus Glycoprotein 2 Antibody:
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1) . Hantavirus glycoprotein precursor (GPC) is posttranslationally cleaved into two glycoproteins G1 (Gn) and G2 (Gc) . While the G1 glycoprotein is is thought to be degraded by the host autophagy machinery, and this autophagic clearance is required for efficient virus repliaction (2) , no such degradation was observed for the G2 glycoprotein.
