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Product Description
CAMK2B Antibody | 18-677 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CAMK2B (NP_742078.1) .
Research Area: Apoptosis, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Tested Application: WB
Application: WB: 1:500 - 1:2000
Specificiy: N/A
Positive Control 1: NCI-H460
Positive Control 2: PC-12
Positive Control 3: Mouse brain
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 51kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: CAMK2B, Beta-subunit of CaMK II, Cam kinase II beta, CaMK IIbeta, CaM-kinase II beta chain, CAMKB, Beta CaMK II, CaM kinase II beta subunit, CaM kinase II subunit beta, CaM kinase IIbeta, CAM2, Camk ii beta, CAMK2, CaMKII beta, CaMK-II subunit beta, CaMKIIbeta
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The product of this gene belongs to the serine/threonine protein kinase family and to the Ca (2+) /calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants.
