Euro
USD
British Pound
NULL
Product Description
PIDD Antibody | 19-480 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human PIDD (NP_665893.2) .
Research Area: Apoptosis, Cancer, Cell Cycle
Tested Application: WB, IF
Application: WB: 1:500 - 1:1000
IF: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: U-87MG
Positive Control 2: 293T
Positive Control 3: K-562
Positive Control 4: Mouse brain
Positive Control 5: Mouse liver
Positive Control 6: Mouse heart
Molecular Weight: Observed: 100-110kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: p53-induced Protein with a Death Domain; Leucine-rich Repeat and Death Domain-containing Protein; Lrdd
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6) -associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD) , and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.
![[One Step] PIDD Antibody Kit](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/396508/574981/unnamed-776x1024__91681.1646254488__92229.1646256048__76401.1646652441.png?c=2 "[One Step] PIDD Antibody Kit")