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Product Description
BNIP3 Antibody | 19-791 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-164 of human BNIP3 (NP_004043.3) .
Research Area: Apoptosis, Autophagy, Cancer, Cell Cycle
Tested Application: WB, IHC, IF
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: MCF7
Positive Control 2: NCI-H460
Positive Control 3: Jurkat
Positive Control 4: SH-SY5Y
Positive Control 5: Mouse kidney
Positive Control 6: Mouse heart
Molecular Weight: Observed: 22-70kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, BNIP3, NIP3
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation.
