Euro
USD
British Pound
NULL
Product Description
LIN28B Antibody | 23-805 | ProSci
Host: Rabbit
Reactivity: Human
Homology: N/A
Immunogen: A synthetic peptide of human LIN28B
Research Area: Cancer
Tested Application: WB, IHC, IF, Flow
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:20 - 1:50
Flow: 1:20 - 1:50
Specificiy: N/A
Positive Control 1: 293
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 27kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, pH7.3.
Concentration: N/A
Storage Condition: Store at 4˚C. Avoid freeze / thaw cycles.
Alternate Name: Protein lin-28 homolog B, Lin-28B, LIN28B, CSDD2
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation.
![LIN28B Antibody [AMM22249G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/870610/1162677/logo__92149.1659788186__33876.1659866737.png?c=2 "LIN28B Antibody [AMM22249G]"){kind=logo}