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Product Description
OTC Antibody | 23-932 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 215-354 of human OTC (NP_000522.3) .
Research Area: Cancer, Signal Transduction
Tested Application: WB, IHC
Application: WB: 1:1000 - 1:4000
IHC: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: Mouse liver
Positive Control 2: Mouse small intestine
Positive Control 3: Rat liver
Positive Control 4: Rat small intestine
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 38kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: OTC, OCTD
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
