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Product Description
GPSM2 Antibody | 13-718 | ProSci
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 380-490 of human GPSM2 (NP_037428.3) .
Research Area: Cell Cycle, Signal Transduction
Tested Application: WB, IHC
Application: WB: 1:1000 - 1:2000
IHC: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: B cells
Positive Control 2: HeLa
Positive Control 3: Mouse brain
Positive Control 4: Mouse liver
Positive Control 5: Mouse kidney
Positive Control 6: N/A
Molecular Weight: Observed: 76kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: GPSM2, LGN, Pins, CMCS, PINS, DFNB82
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82) . Alternative splicing results in multiple transcript variants.
