Euro
USD
British Pound
NULL
Product Description
PCDHB16 Antibody | 16-072 | ProSci
Host: Rabbit
Reactivity: Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 29-90 of human PCDHB16 (NP_066008.2) .
Research Area: Cell Cycle, Neuroscience, Signal Transduction
Tested Application: WB
Application: WB: 1:200 - 1:2000
Specificiy: N/A
Positive Control 1: Mouse brain
Positive Control 2: Rat brain
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 85kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: ME1, PCDH-BETA16, PCDH3X, PCDHB8a, protocadherin beta-16, cadherin ME1, protocadherin beta 8a, protocadherin-3x
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
