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Product Description
SGCD Antibody | 22-603 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 61-290 of human SGCD (NP_000328.2) .
Research Area: Cell Cycle, Signal Transduction
Tested Application: WB, IHC, IF
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
IF: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: Jurkat
Positive Control 2: THP-1
Positive Control 3: Mouse heart
Positive Control 4: Mouse skeletal muscle
Positive Control 5: Rat heart
Positive Control 6: Rat skeletal muscle
Molecular Weight: Observed: 37kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: dystrophin associated, delta-sarcoglycan, delta-SG, 35kD dystrophin-associated glycoprotein, SGD, SGCDP, SG-delta, MGC22567, DAGD, CMD1L, 35DAG, sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) , SGCD
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC) . DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
