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Product Description
CCL4 Antibody | XW-7720 | ProSci
Host: Chicken
Reactivity: Human
Homology: N/A
Immunogen: 27-92
Research Area: Chemokines & Cytokines
Tested Application: E, WB
Application: Small inducible cytokine A4 antibody can be used for the detection of Small inducible cytokine A4 by ELISA and Western Blot, may also work for ICC and IHC.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 10.2 kDa (calculated)
Validation: N/A
Isoform: N/A
Purification: Immunoaffinity Purified
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Condition: CCL4 antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: LAG1, MIP1B, SCYA4, C-C motif chemokine 4, G-26 T-lymphocyte-secreted protein, LAG-1, ACT2, G-26, HC21, LAG1, SCYA2, MIP1B1, AT744.1, MIP-1-beta, Small inducible cytokine A4, CCL4, Macrophage inflammatory protein 1-beta, MIP-1-beta (1-69) , T-cell activation protein 2, ACT-2, PAT 744, H400, SIS-gamma, Lymphocyte activation gene 1 protein, G-26 T lymphocyte-secreted protein
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: FUNCTION: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T cells. Recombinant MIP-1-β induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV) . The processed form MIP-1-β (3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T cells. MIP-1-β (3-69) is also a ligand for CCR1 and CCR2 isoform B.
